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مرضیه کافشانی، محمد حسن انتظاری، زهرا السادات خسروی

Introduction: vitamin D deficiency has defined as a health problem in the worldwide. Recently, it has been shown that vitamin D deficiency may be related to insulin sensitivity, hypertension, hyperlipidemia, and obesity. These factors are linked to increased risks of serious health complications such as type 2 diabetes, CVD, stroke, and kidney failure. In this study, we aimed to perform an investigation about the effects of vitamin D supplementation on anthropometric indices, lipid profile, and blood pressure on obese and overweight women. Subject and method: This double blind clinical trial was done on 53 overweight and obese women who divided into two groups which intervention group received vitamin D supplements with dozes 50000 IU/w for 6 weeks and another received placebo. The anthropometric indices, biochemical markers, and blood pressure measured before and after intervention, and independent- samples t- test and paired- samples t- test were used to compare the mean between and within group respectively. Results: After using vitamin D supplementation for 6 weeks weight (wt), WC, Body Mass Index (BMI) were decreased significantly and serum vitamin D increased significantly compared to control group (p<0/001). Other factors including total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDLc), high density lipoprotein cholesterol (HDLc), and WHR did not change significantly (p>0/05). Discussion: The evidence of this study suggests that supplementation of the vitamin D with dozes 50000 IU/w for 6 weeks in obese and overweight women lead to reduce in BMI, weight and WC significantly, whilst this study did not confirm the effect of vitamin D supplementation on lipid profile. .

Vitamin D Supplementation, Anthropometric indices, Cholesterol, LDL- Cholesterol, HDL- Cholesterol, Triglyceride, Blood pressure

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کافشانی، مرضیه، حسن انتظاری، محمد، السادات خسروی، زهرا، 1400، مکمل ویتامین D بر روی شاخص های تن سنجی اثر می گذارد اما روی پروفایل لیپیدی و فشارخون بی اثر است، سیزدهمین کنگره قلب و عروق خاورمیانه و ششمین همایش مداخلات پیچیده قلبی، http://conf.sums.ac.ir/fa/archive_index.php?c=HN-mecc13&aid=1512541